Apostdoctoral fellow position is available immediately in the Department of Microbiology,Immunology and Biochemistry at the University of Tennessee Health ScienceCenter. The faculty mentor for this position is Dr. Ae-Kyung Yi. We are lookingfor a highly motivated, recently graduated Ph.D. with expertise in molecular biologyand biochemistry or related area to study the molecular mechanism of patternrecognition receptor signal transduction and the relationship(s) between hostinnate immunity and the pathogenesis of acute and chronic inflammatorydiseases. Currently, the focus of the lab is to investigate the molecularmechanisms of a pattern recognition receptor (especially TLR and IL-1R familyreceptors) signaling pathway and the role of a signaling modulator in a patternrecognition receptor signaling in the pathogenesis of chronic autoimmunediseases, such as arthritis and SLE, and in acute and chronic inflammatorydisorders, including sepsis and hypersensitivity pneumonitis. The main functionwill be studying protein-protein interactions, intracellular localization ofpattern recognition receptor signaling components, identifying structure-functionrelationship of signaling molecules, and investigating a molecular mechanism ofpattern recognition receptor signal transduction and its impact on chronicinflammatory diseases.
Internal Number: 128626
The mission of the University of Tennessee Health Science Center is to bring the benefits of the health sciences to the achievement and maintenance of human health, with a focus on the citizens of Tennessee and the region, by pursuing an integrated program of education, research, clinical care, and public service.