A postdoctoral fellow position is available immediately in the Department of Microbiology, Immunology and Biochemistry at the University of Tennessee Health Science Center. The faculty mentor for this position is Dr. Ae-Kyung Yi. We are looking for a highly motivated, recently graduated Ph.D. with expertise in molecular biology and biochemistry or related area to study the molecular mechanism of pattern recognition receptor signal transduction and the relationship(s) between host innate immunity and the pathogenesis of acute and chronic inflammatory diseases. Currently, the focus of the lab is to investigate the molecular mechanisms of a pattern recognition receptor (especially TLR and IL-1R family receptors) signaling pathway and the role of a signaling modulator in a pattern recognition receptor signaling in the pathogenesis of chronic autoimmune diseases, such as arthritis and SLE, and in acute and chronic inflammatory disorders, including sepsis and hypersensitivity pneumonitis. The main function will be studying protein-protein interactions, intracellular localization of pattern recognition receptor signaling components, identifying structure-function relationship of signaling molecules, and investigating a molecular mechanism of pattern recognition receptor signal transduction and its impact on chronic inflammatory diseases.
Qualifications Ph.D. with a strong background in biological sciences (biochemistry, molecular biology, cell biology, immunology, microbiology, pathology, physiology). Research experience in areas useful to studies of cell signal transduction, innate immune response, inflammation, and autoimmune disease. Basic understanding of and experience with ELISA assays, Western blot analysis, protein-protein interactions, peptide library construction and screening, in vitro kinase assays, PCR, RT-PCR, real-time PCR, gene cloning, site-directed mutagenesis, siRNA, CRISPR, in-situ hybridization, gene chip analysis, CHIP assays, cellular transfection, tissue culture, FACS, confocal microscopy, viral gene delivery system, and database searches. Ability to work with rodents. Ability to learn and develop new techniques, whenever necessary. Good communication and writing skills. Send curriculum vitae and the names and contact information of three references to Dr. Ae-Kyung Yi, Associate Professor, Department of Microbiology, Immunology and Biochemistry, UTHSC. E-mail: email@example.com or apply on-line Salary will be commensurate with relevant experience and is competitive for postdoctoral research fellows. The position includes an excellent benefits package (http://www.uthsc.edu/postdoc/benefits.php). Located in Memphis, a dynamic Mid-South city rich in culture, history, diversity, music and cuisine, the University of Tennessee Health Science Center is one of the largest, most comprehensive academic health centers in the United States with a solid commitment to postdoctoral training. UTHSC is an EEO/AA/Title VI/Title IX/Section 504/ADA/ADEA/V institution in the provision of its education and employment programs and services.
The mission of the University of Tennessee Health Science Center is to bring the benefits of the health sciences to the achievement and maintenance of human health, with a focus on the citizens of Tennessee and the region, by pursuing an integrated program of education, research, clinical care, and public service.